![]() ![]() Rapid genotyping of blood recipients and rapid donor sequencing is transforming personalized transfusion medicine. In transfusion medicine, blood banking, and cellular therapy, as in virtually every field of medicine, next-generation genomic sequencing (NGS) is revolutionizing practice. Mills Barbeau MD, JD, in Risk Management in Transfusion Medicine, 2019 A Test Case: Incidental Findings in Next-Generation Sequencing 10 Greater involvement could also enhance the ability to continuously monitor for new data and adverse events that would necessitate changing these practices, and rapidly make the appropriate adjustments to minimize transfusion risks in vulnerable pediatric patients. Increasing the involvement of pediatric specialists in transfusion committees and patient blood management systems can help to create consensus, and standardize pediatric transfusion practices. Despite these limitations, pediatric institutions must discourage highly variable, practitioner dependent, transfusion decisions that further impede quality improvement efforts. In addition, a lack of randomized controlled clinical studies in pediatric populations relative to adult populations necessitates that risk management decisions rely on conclusions from retrospective data that is subject to bias from confounding variables. The identification and prioritization of risks in pediatric transfusion medicine requires specialized knowledge of pediatric physiology, disease states, and genetics. Pediatric transfusion medicine presents unique challenges in risk management because the potential impact of risk is far greater in younger patients, and as body size decreases, medical fragility increases and the number of risks multiples. Weisberg MD, PhD, Sarah Vossoughi MD, in Risk Management in Transfusion Medicine, 2019 Abstract BB/TM physicians should be advocates for the best transfusion care of patients and the best care of donors, be teachers and mentors, and be devoted to the continual improvement of the field of BB/TM. ![]() There are multiple career options in the field of BB/TM, with wide-ranging opportunities including clinical, teaching, research and administration. A recent survey demonstrated that approximately 70% of BB/TM fellowship graduates from 1995–2004 had published articles within the previous 3 years, and 12% had published over 10 publications within that timeframe. BB/TM physicians participate in research, including basic and translational investigations, cellular therapy, blood donation and transfusion issues, and clinical trials. BB/TM physicians continue to participate in expanding areas outside the hospital transfusion service and donor program, such as HLA laboratory, HPC collection and processing laboratory, tissue banking, and coagulation laboratory direction. Hillyer MD, in Transfusion Medicine and Hemostasis, 2009 TM as a Career:īlood banking and transfusion medicine (BB/TM) physicians work in a variety of settings, including blood centers, hospital transfusion services, industry, government, and large commercial laboratories. Chapters 17–77 Chapter 17 Chapter 77 are dedicated to “transfusion medicine.”īeth H. The hospital transfusion service is also typically responsible for consultation to clinicians regarding complex transfusion and coagulation issues, and the choice of specialized products including recombinant and human-derived coagulation-related concentrates, intravenous gammaglobulin and albumin. The AABB (formerly the American Association of Blood Banks) Standards define these activates as simply a “transfusion service,” since a number of blood centers will also perform these functions or offer these services. Transfusion medicine thus occurs predominately in hospitals usually under the FDA designation at registration as a hospital transfusion service. Transfusion medicine most often connotes pretransfusion and compatibility testing post-manufacture processing, including irradiation, washing and volume reduction and administration of appropriate products to the appropriate patients. Hillyer MD, in Transfusion Medicine and Hemostasis, 2009 Transfusion Medicine Defined: ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |